a successful career in research requires careful planning
with the right project supervised by an experienced mentor, a supportive
environment with excellent resources, and a proven track record
in training outstanding investigators. The Infectious Diseases
Division has all of the tools and resources to prepare our fellows
to be outstanding physician scientists. The Division shares in
the wonderful heritage and legacy of Washington University School
of Medicine, one of the premier research institutions in the world
whose mission is to train future leaders in medicine and science.
It is a particularly propitious time for training in clinical and
translational research at Washington University. The University
has recently been awarded a multimillion-dollar NIH K12 grant to
establish a formal Multidisciplinary Clinical Research Career Development
Program (MCRCDP) that involves multiple departments and programs
at Washington University in collaboration with St. Louis University
School of Public Health. MCRCDP, a multidisciplinary effort, is
headed by Victoria Fraser, Co-Director of Infectious Diseases and
will be integrated and coordinated with existing programs to promote
clinical and translational research training resulting in a Master’s Degree in Clinical Investigation
or a Master’s Degree in Public Health for scholars who enroll
in the program (see link for complete description of this program).
Washington University also has an NIH K30 program which provides
a two- year didactic curriculum in clinical research for fellows
and junior faculty leading to a Master’s Degree in Clinical
Investigation (Brad Evanoff, Principal Investigator). In addition,
there is an NIH T32 Predoctoral Clinical Research Training
Grant here to provide clinical research training for medical and
Ph.D. students (Jay Picirillo, Principal Investigator).
The main focus of training in laboratory-based research is centered
on the Divisions of Adult Infectious Diseases (Department of Internal
Medicine), and Pediatric Infectious Diseases (Department of Pediatrics)
and the Department of Molecular Microbiology. All three units are
situated in a block on floors 6-10 of the McDonnell Pediatric Research
Building, the Center for Infectious Diseases Research. Throughout
the Center there are open stairways and shared conference rooms
to facilitate interactions. Other participating labs of the Department
of Internal Medicine and the Department of Immunology and Pathology
are in close proximity. This remarkable concentration of infectious
diseases/microbiology-focused investigators has fostered a vibrant,
highly interactive and collaborative environment.
research program of the Infectious Disease Division is supported
by an NIH Training Grant which has been in existence since 1971.
The Division has over 20 million dollars in grant support which
provides the resources necessary to support an exciting and diverse
spectrum of research projects. Research in the Division is also
supported via the Midwest Regional Center of Excellence for Biodefense
and Emerging Infectious Diseases Research (MRCE), a NIH funded
center with an annual budget of over 8 million dollars founded
at Washington University in 2003. The outstanding support for
research generated by investigators in the Division is the best
proof of the quality and breadth of the research projects that
are available for participation by our fellows. Therefore, our
fellows can choose to work on an incredibly broad and diverse
spectrum of research topics.
research agenda is divided into two major research programs.
The clinical program is headed by Victoria Fraser and features
major programs in HIV/AIDS Clinical Trials, Healthcare Epidemiology,
Informatics, Pharmaco-epidemiology, Sexually Transmitted Diseases,
Patient Safety, vaccine research and Clinical Microbiology and
Virology. Multidisciplinary research training is supported by
the NIH K12 MCRDP Center Grant directed by Dr. Fraser as well
as grants from the CDC, AHRQ, HRSA and NIH. Dan Goldberg leads
the basic science research agenda which contains major programs
in molecular pathogenesis, immunopathogenesis, molecular microbiology,
parasitology, mycology, virology, biodefense and emerging infections.
Dr. Goldberg also directs the MSTP Program at Washington University
which is the largest MD/PhD Program in the country. All of the
faculty in laboratory based research have joint appointments
in the Department of Molecular Microbiology and participate in
joint research programs, journal clubs and research seminars.
Several of the faculty have joint appointments in other basic
science departments. Translational research is done by individual
basic science or clinical faculty and is an important bridge
connecting the research interests of both components.
The faculty of the Infectious Diseases
Division and relevant faculty from other departments participating
in the research program of the Division are listed below in the
faculty section with links to description of their individual research
interests and recent relevant publications. Our fellows are also
free to work with any other faculty member in the University, should
their research interests not be met by the faculty in our program.